The Biochemical Basis of Neuropharmacology

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Oxford University Press, 2003 - Medical - 405 pages
This classic text gives a uniquely lucid and lively view of neurotransmitters, their role in nervous system function, and their involvement in the mechanisms of psychiatric drug action. For three decades it has served as an essential guide for students of neuroscience and psychopharmacology, residents in psychiatry and neurology, and clinicians and scientists. Both authoriative and very readable, it has been thoroughly updated for each edition. In the 8th Edition more space is devoted to clinical examples, subclasses of receptors that provide targets for new drugs, molecular genetics, the major problem of drug delivery to the brain, and the growing recognition of nicotin receptors in the brain and their possible involvement in Alxheimer's and Parkinson's diseases. In addition, the book's format has been enlarged and a second color added to many of the illustrations.
 

Contents

Introduction
1
Cellular Foundations of Neuropharmacology
7
Molecular Foundations of Neuropharmacology
39
Receptors
65
Modulation of Synaptic Transmission
85
Amino Acid Transmitters
105
Acetylcholine
149
Norepinephrine and Epinephrine
179
Dopamine
223
Serotonin 5Hydroxytryptamine Histamine and Adenosine
269
Neuroactive Peptides
319
Cellular Mechanisms in Learning and Memory
355
Treating Neurological and Psychiatric Diseases
371
Index
399
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Page 354 - Overproduction of corticotropin-releasing factor in transgenic mice: A genetic model of anxiogenic behavior. J Neurosci 14: 2579-2584, 1994.

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