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ENVI Committee exchange of view
Vaccination in the EU:
benefits and barriers
Prof Mike Catchpole, Chief Scientist
European Centre for Disease Prevention and Control
ENVI Committee 17 June 2015, European Parliament, Brussels
December 2004 October 2012
Why do EU Member States have vaccination programmes?
To protect the health of Europeans
Finland - reported measles, mumps, and rubella through November,
2007, since 1915 for measles, 1943 for mumps, and 1957 for rubella*
*Peltola et al Measles, mumps, and rubella in Finland: 25 years of a nationwide elimination programme Lancet 2008; issue 8 vol 12; 796–803
Through MMR vaccination
measles complications averted
Hospitalisations: 1 per 5 cases
Otitis media: 1 per 11 cases
Pneumonia: 1 per 12 cases
Encephalitis: 1 per 1,000 cases
Subacute sclerosing panencephalitis: 1 per
100,000
Deaths: 1 per 1,000 to 5,000 cases
mumps complications averted
Hospitalisations: 1 per 25 cases
Meningitis: 1 per 12 cases
Bilateral orchitis: 1 per 30 cases
Encephalitis: 1 per 300 cases
Pancreatitis: 1 per 500 cases
Hearing impairment: 1 per 300 to 1,000
cases
rubella complications averted
Congenital rubella syndrome: 1 per 400
cases
Post-infectious encephalopathy: 1 per
500,000 cases
Vaccines used in EU are highly safe
Vaccination in the EU, ENVI Committee, European Parliament 17 June 2015
Vaccination policy in Europe is
not achieving its public health goals
Example: elimination of measles in Europe by 2010, 2015, 2020 (?!)
Source: TESSy data on measles cases reported 1 January – 30 April 2015;
Measles vaccine coverage (two doses, 2012 – 2013)
EU citizens still die from vaccine
preventable diseases! The threat continues
Why vaccination targets are not met (1):
Vaccine hesitancy
• Influenced by issues of confidence (level of trust in vaccine or
provider), complacency (do not perceive need for vaccine) and
convenience (access).
• Hesitant citizens may: i) accept all vaccines but remain concerned; or
ii) refuse or delay some vaccines; or iii) refuse all vaccines
• Results of the ECDC study:
– Main concern/ fear: vaccine safety
– Hesitancy among healthcare professionals
Vaccine safety
concerns
Incidence of disease
Source: Rapid literature review on motivating hesitant population groups in Europe to vaccinate, ECDC, 2015
(under editing).
Why vaccination targets are not met (2):
Under-served population groups
Photo credits: www.vam.ac.uk/moc/images/image/36307-popup.html, by Eithne Nighingale
http://www.flickr.com/photos/87563734@N00/ by Henri Weisen
Why vaccination targets are not met (3):
Vaccine availability
• Currently, almost one third of Member States have reported
difficulties in procuring vaccines for the vaccination of infants
against pertussis (whooping cough).
• Three out of nine influenza vaccine producers in EU closed
production in the last two years (Baxter, Crucell &
Cantacuzzino).
Strengthening prevention and control:
What ECDC is currently doing
2015 will aim at:
 Supporting in responding to the existing and
upcoming Council Conclusions on immunisation
 Providing evidence-based communication tools for
reaching hesitant groups
 Fostering exchange of knowledge to strengthen
vaccination programmes - VENICE project
 Coordinating and supporting EU-wide VPD network
 Supporting Member States with country visits upon
request
ECDC works in a multi-disciplinary approach…
…to support and strengthen prevention and control efforts on
vaccine preventable diseases (VPDs) in the EU/EEA.
What more can be done at EU level?
• Support for EU level projects on key issues such as:
– vaccine hesitancy
– under-served populations
– immunity gaps etc.
• EU action to further improve evidence-base for public health
(national and EU level) decisions on vaccination policy
– ECDC guidance
– Robust vaccine monitoring data

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Vaccination in the EU, ENVI Committee, European Parliament 17 June 2015

  • 1. ENVI Committee exchange of view Vaccination in the EU: benefits and barriers Prof Mike Catchpole, Chief Scientist European Centre for Disease Prevention and Control ENVI Committee 17 June 2015, European Parliament, Brussels
  • 2. December 2004 October 2012 Why do EU Member States have vaccination programmes? To protect the health of Europeans
  • 3. Finland - reported measles, mumps, and rubella through November, 2007, since 1915 for measles, 1943 for mumps, and 1957 for rubella* *Peltola et al Measles, mumps, and rubella in Finland: 25 years of a nationwide elimination programme Lancet 2008; issue 8 vol 12; 796–803 Through MMR vaccination measles complications averted Hospitalisations: 1 per 5 cases Otitis media: 1 per 11 cases Pneumonia: 1 per 12 cases Encephalitis: 1 per 1,000 cases Subacute sclerosing panencephalitis: 1 per 100,000 Deaths: 1 per 1,000 to 5,000 cases mumps complications averted Hospitalisations: 1 per 25 cases Meningitis: 1 per 12 cases Bilateral orchitis: 1 per 30 cases Encephalitis: 1 per 300 cases Pancreatitis: 1 per 500 cases Hearing impairment: 1 per 300 to 1,000 cases rubella complications averted Congenital rubella syndrome: 1 per 400 cases Post-infectious encephalopathy: 1 per 500,000 cases
  • 4. Vaccines used in EU are highly safe
  • 6. Vaccination policy in Europe is not achieving its public health goals Example: elimination of measles in Europe by 2010, 2015, 2020 (?!) Source: TESSy data on measles cases reported 1 January – 30 April 2015; Measles vaccine coverage (two doses, 2012 – 2013)
  • 7. EU citizens still die from vaccine preventable diseases! The threat continues
  • 8. Why vaccination targets are not met (1): Vaccine hesitancy • Influenced by issues of confidence (level of trust in vaccine or provider), complacency (do not perceive need for vaccine) and convenience (access). • Hesitant citizens may: i) accept all vaccines but remain concerned; or ii) refuse or delay some vaccines; or iii) refuse all vaccines • Results of the ECDC study: – Main concern/ fear: vaccine safety – Hesitancy among healthcare professionals Vaccine safety concerns Incidence of disease Source: Rapid literature review on motivating hesitant population groups in Europe to vaccinate, ECDC, 2015 (under editing).
  • 9. Why vaccination targets are not met (2): Under-served population groups Photo credits: www.vam.ac.uk/moc/images/image/36307-popup.html, by Eithne Nighingale http://www.flickr.com/photos/87563734@N00/ by Henri Weisen
  • 10. Why vaccination targets are not met (3): Vaccine availability • Currently, almost one third of Member States have reported difficulties in procuring vaccines for the vaccination of infants against pertussis (whooping cough). • Three out of nine influenza vaccine producers in EU closed production in the last two years (Baxter, Crucell & Cantacuzzino).
  • 11. Strengthening prevention and control: What ECDC is currently doing 2015 will aim at:  Supporting in responding to the existing and upcoming Council Conclusions on immunisation  Providing evidence-based communication tools for reaching hesitant groups  Fostering exchange of knowledge to strengthen vaccination programmes - VENICE project  Coordinating and supporting EU-wide VPD network  Supporting Member States with country visits upon request ECDC works in a multi-disciplinary approach… …to support and strengthen prevention and control efforts on vaccine preventable diseases (VPDs) in the EU/EEA.
  • 12. What more can be done at EU level? • Support for EU level projects on key issues such as: – vaccine hesitancy – under-served populations – immunity gaps etc. • EU action to further improve evidence-base for public health (national and EU level) decisions on vaccination policy – ECDC guidance – Robust vaccine monitoring data

Editor's Notes

  • #3: Max, 18 year old, victim of Subacute Sclerosing Pan-Encephalitis in 2012. Max died in 2014 http://www.vaccinestoday.eu/vaccines/how-measles-can-change-a-life/
  • #9: Vaccine hesitancy = a behaviour, influenced by a number of factors including issues of confidence [level of trust in vaccine or provider], complacency [do not perceive a need for a vaccine, do not value vaccine] and convenience [access]. - May accept all vaccines but remain concerned, may refuse or delay some vaccines or may refuse all vaccines Results of the ECDC study: Main concern/ fear: vaccine safety Hesitant vaccine providers and healthcare professionals ECDC’s next steps: a qualitative study under implementation publish all results in a comprehensive report design a communication guide
  • #10: Photos: irregular migrants (top left), the Roma (right) and travelling communities (bottom left) Some population groups have limited or difficult access to preventative services due to: social exclusion; poverty; convenience ECDC implemented an action plan on measles and rubella, to contribute to the WHO targets on eliminating these One area of this plan was capacity building at the MS level; ECDC designed and implemented pilot projects targeting the under-served population groups, mainly Roma. These projects were aimed at equipping the healthcare professionals with communication tools to be used in their daily practice when addressing vaccination topics with parents and grandparents.