Phase behavior of lipid mixtures

Nat Chem Biol. 2006 Nov;2(11):560-3. doi: 10.1038/nchembio1106-560.

Abstract

Biological membranes are two-dimensional mixtures of an enormous number of different components. Modeling cell membranes as simple bilayer mixtures reveals rich phase behavior, but how can we use the observed phase behavior to understand the real membranes?

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Animals
  • Cell Membrane / chemistry*
  • Cell Membrane / physiology
  • Cholesterol / chemistry*
  • Cholesterol / physiology
  • Humans
  • Lipid Bilayers / chemistry
  • Lipid Bilayers / metabolism
  • Lipids / chemistry*
  • Lipids / physiology
  • Models, Chemical
  • Molecular Structure
  • Phase Transition
  • Phosphatidylcholines / chemistry*
  • Phosphatidylcholines / physiology
  • Surface Properties

Substances

  • Lipid Bilayers
  • Lipids
  • Phosphatidylcholines
  • Cholesterol
  • 1,2-distearoyllecithin
  • 1,2-oleoylphosphatidylcholine