A lectin from elder (Sambucus nigra L.) bark

Biochem J. 1984 Jul 1;221(1):163-9. doi: 10.1042/bj2210163.

Abstract

A lectin was isolated from elder (Sambucus nigra) bark by affinity chromatography on fetuin-agarose. It is a tetrameric molecule (Mr 140000) composed of two different subunits of Mr 34500 and 37500 respectively, held together by intramolecular disulphide bridges. The lectin is a glycoprotein and is especially rich in asparagine/aspartic acid, glutamine/glutamic acid, valine and leucine. It is also the first lectin isolated from a species belonging to the plant family Caprifoliaceae.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acids / analysis
  • Carbohydrates
  • Chemical Phenomena
  • Chemistry
  • Chromatography, Affinity
  • Chromatography, Gel
  • Electrophoresis, Polyacrylamide Gel
  • Hemagglutination / drug effects
  • Lectins / isolation & purification*
  • Lectins / pharmacology
  • Protein Biosynthesis / drug effects

Substances

  • Amino Acids
  • Carbohydrates
  • Lectins